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Together, these multiple mechanisms contribute to the efficacy of daratumumab, which was proven in the subsequent clinical trials as an effective and durable antitumor drug in MM patients

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Deregulated activation of c-Met contributes to a few aspects of tumor progression, such as inducing neoplastic cells to disaggregate from the tumor mass, eroding basement membranes, infiltrating stromal matrices, and finally colonizing new tissues to form metastases ( Onset Chronic liver diseases such as cirrhosis and hepatitis B or C are triggers of HCC (Janevska et al., 2015)

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As part of this initiative, our team had the opportunity to support the study comprehensively across its full lifecyclereinforcing the value of rigorous late-phase research in real-world clinical environments
