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Description
In contrast to HO-1, the HO-2 isozyme is constitutively expressed, highly detectable in brain, testis, endothelial and smooth muscle cells from cerebral vessels
To address these issues, researchers have developed Pt ()-based prodrugs
Feinberg Andrew et al., 2023
doi: 10.1016/j.micpath.2019.103792
SCI vs SCI+GlyNAC, P = 0.6916)
While the depletion of cysteine and the accumulation of cystine and Met-SO clearly indicate increased oxidative stress in SLE, none of these compounds or the unique PPP substrates R5P or S7P correlated with disease activity of untreated patients
