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Clinical trials would need an IND protocol

If you notice adverse effects (e.g., increased nighttime awakenings, headaches, mood shifts, altered blood pressure, hormonal imbalance) reduce dose or discontinue and consult a qualified specialist

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These combined effects suggest that it influences neural recovery through a multifactorial biological framework rather than a single target mechanism (15)

55 MiR-182-5p directly inhibits the expression of FOXO3a, preventing its binding to -catenin, enhancing the interaction between -catenin and TCF4, and then promoting canonical Wnt signalling