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These processes play a crucial role in the biological mechanisms that drive tissue development, such as the regulation of cell polarity, gene expression and stem cells differentiation (Smith et al., 2018)

[DOI] [PubMed] [Google Scholar] Tarasava K

Many therapies targeting various physiological processes have been explored for primary mitochondrial disease, including the application of antioxidants to mitigate mitochondrial and cellular oxidative stress [94]

Aging diminishes tissue renewal and impairs repair across organs, each employing unique strategies

Interestingly, the mitochondrial form of GTK/KAT I is identical to the cytosolic form except that the former contains an additional stretch of 32 amino acids at the N-terminus (Malherbe et al., 1995)

31433153, 2013 [39] R