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Indeed, HGF increases the proliferation of cerebellum granule cell precursors and this effect is reduced in a hypomorphic MET mutant (Grb2-binding incompetent) that leads to a smaller size of the cerebellum (Ieraci et al., 2002)
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Thus, when GPx4 expression was suppressed by siRNA-mediated knockdown between gestational day E7.5 and E10.5 abnormal development of mid and hindbrain structures was observed (Figure 3
No blood sample has been collected, submitted, or processed
USA 112 , 1385013855 (2015)
