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The general clinical principle is that obesity is a chronic disease, and like blood pressure or diabetes medications, weight loss medications often need to continue long-term to maintain results

When, despite transformation, model fit was insufficient (hypoglycaemic and hyperglycaemic outcomes), the period-adjusted sign test (as described by Senn) was used [41]

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Always consult your prescribing provider before starting, adjusting, or stopping this therapy

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