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Results Administration of exogenous melatonin alleviates allergic airways disease severity in allergen-exposed mice Given the growing evidence linking circadian disruption to increased severity of allergic asthma (9, 12, 14, 26, 27), we investigated whether exogenous melatonin could modify disease outcomes in a murine model of allergic airways inflammation

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Damage of this type affects aconitase and isopropylmalate isomerase, for example, and thereby impairs the TCA cycle and the synthesis of branched-chain amino acids (Jang and Imlay, 2007)

These attributes significantly enhance the reliability and quality of findings in peptide research

Cell 119:941953 Shi Y, Tomic J, Wen F, Shaha S, Bahlo A, Harrison R, Dennis JW, Williams R, Gross BJ, Walker S et al (2010) Aberrant O-GlcNAcylation characterizes chronic lymphocytic leukemia