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Citing these recent works will both address the reviewers concern about currency and strengthen the argument that GSH-responsive strategies are maturing toward precision, clinically relevant theranostics [20]

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Teskey G, Abraham R, Cao R, Gyurjian K, Islamoglu H, Lucero M, Martinez A, Paredes E, Salaiz O, Robinson B, Venketaraman V

Influence of comorbidities and age on risk of death without recurrence: a retrospective analysis of the Arimidex, Tamoxifen Alone or in Combination trial

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Could glutamate destined for oxidation and for glutamine synthesis be segregated, and the pathways suggested in Figure 3A apply only to the former