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The rats were maintained in an animal room with an air-conditioned barrier system at an ambient temperature of 25C 2C, relative humidity of 50% 10%, and a 12 h light/dark cycle

Patients with severe heart failure or arrhythmias require monitoring because rapid shifts in free-fatty-acid metabolism can influence myocardial substrate utilization

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However, subcutaneous injection remains the most reliable administration route for consistent dosing

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