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Since both glucose and fatty acids could contribute to histone acetylation, we reasoned that this could occur either by two distinct substrate-specific mechanisms or a mechanism in which these substrates can feed into a common precursor acetyl-CoA pool (e.g., in mitochondria) that is then transported to the nuclear-cytosolic compartment (Supplemental Figure 5E)

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[DOI] [PubMed] [Google Scholar] Trumbeckaite S, Opalka JR, Neuhof C, Zierz S, Gellerich FN

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