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Oral KPV formulations showed 40% reduction in Disease Activity Index scores in murine IBD models vs 15% placebo response

Once diagnosed, Suzie was treated with hydroxocobalamin, an injectable form of B12, with eight 1 mg doses over three weeks (injections are given in more severe cases to ensure it is absorbed straight into the bloodstream) Suzie had shown initial improvement with the higher dose of B12, but deteriorated fast when the dose was dropped, and had to move in with her parents

CYANOCOBALAMIN INJECTION, USP 1000 mcg/mL Sterile (Vitamin B12) [Label]

Vitamin B12 Regulates Cytokines and Neurotrophic Factors A very new research field has brought to light astonishing new functions of B12 in the nervous system, which go far beyond its role as coenzyme and rather resemble the mode of action of a hormone: vitamin B12 regulates the level of certain neurotrophic factors such as neurotransmitters, growth factors and the so-called cytokines essential messenger substances that all assume a controlling function in numerous bodily processes (32)

I feel a big difference for the better
