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AP-1 regulates many of the inflammatory and immune genes in oxidant-mediated diseases

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In this field, a crucial inflammatory factor, IL-1, was observed downregulated by Lactobacillus gasseri NK109 with the simultaneous upregulated expression of brain-derived neurotrophic factor (BDNF) in the hippocampus of mice with cognitive impairment and depression induced by Escherichia coli K1, suggesting its alleviation in brain inflammation against neuropsychiatric disorders caused by bacterial infection [86]

Consistently, colonocytes from germ-free mice show a metabolic shift from OXPHOS to glycolysis 93 and concomitantly, diminished cell cycle progression 115

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IV therapy may be appropriate for adults seeking hydration and nutrition support through medically guided care