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Elevated Hcy can further aggravate renal injury by inducing oxidative stress (47), insufficient autophagy and renal aging (48), forming a negative feedback loop

doi: 10.1111/j.1365-2796.2010.02341.x [DOI] [PubMed] [Google Scholar] 413

For example, it has been recently shown that curcurbitacin I, a potent anticancer molecule, induced an autophagy process in GBM cells and in a xenograft model, leading to cell survival and tumor protection

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