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These results suggested that the associated protective role of Ppara Hep mice in APAP-induced liver injury was not due to APAP bioactivation and detoxification
In conclusion, NAC use to improve renal outcomes in general surgery may be limited to instances of contrast-induced nephropathy, with minimal evidence for renal benefit in non-contrast surgeries
For example, the yearly recurrence rate of hepatocellular carcinoma (HCC) post-surgical resection equals or exceeds 10% and escalates to between 70 and 80% after five years [292]

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[DOI] [PubMed] [Google Scholar] 78.Deng L Du C Song P Chen T Rui S Armstrong DG, et al

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