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PubChem CID 73587 molecular weight 340.38 g/mol

The most advanced of these candidates, Biogens antisense oligonucleotide BIIB080, is in Phase 2 trials that will wrap up this year

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To imitate hemorrhage toxicity in vitro , the model was constructed by applying 100 M hemin to Astrocytes ( Synthetic RNA Oligonucleotides and Transfection We purchased miRNA-146a-3p mimics, miRNA-146a-3p inhibitors, and a non-sense sequence for use as a miRNA negative control (NC) from Genepharma (Shanghai, China) (Supplementary Table 2)

Shi et al., 2025) and intensified inflammatory responses (Wei et al., 2024), which further limit the efficiency of drug delivery