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Fatty Acids 2012, 87, 135141

Potential Harm: NAC: Nausea, vomiting (oral)

These biological effects are mediated through the Vitamin D Receptor (VDR), a ligand-activated nuclear transcription factor expressed in metabolically active tissues, including intestinal epithelial cells, adipose tissue, and pancreatic beta-cells (Carlberg and Campbell, 2013)

10.1371/journal.pone.0113087 PLoS One 156 ZhouT.YanL.XieC.LiP.JiangL.FangJ.et al (2019)

Brain Res (2000) 887:809

As if this weren't enough, NAC and milk thistle supplements help maintain cytokine levels already-within a normal range and encourage a healthy inflammatory response