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In the experiments, we used physiological concentrations of quercetin, (-)-epicatechin, and ibuprofen (Sigma, USA)
Niacinamide blocks melanin transfer

Fang developed a multifunctional targeting nanoplatform (DOX/Au-Apt@ZIF-8) based on the MOF (ZIF-8), combining doxorubicin, the AS1411 aptamer, and gold nanorods to achieve a synergistic anti-tumor effect through chemotherapy, targeting, and photothermal therapy (Fang et al., 2024)

Melanin is the prominent reason behind the darkening of the skin
Role of Nrf2 and p62/ZIP in the neurite outgrowth by carnosic acid in PC12h cells