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Prostaglandin modulation of the gastric vasculature and mucosal integrity in cirrhotic rats

10.1016/j.mpmed.2023.02.005

MAGMA 35:9971008

First synthesized as designer opioids in the 1950s by CIBA Aktiengesellschaf, a Swiss pharmaceutical company in search of alternative analgesic agents, nitazenes were quickly discovered to have high abuse potential

Some practitioners report using 4 to 5 mg per injection twice weekly (8 to 10 mg per week) for severe or long-standing injuries

In addition, SGECs from SS are more sensitive to apoptosis than healthy controls (44, 55, 56), whereas ductal cells express the anti-apoptotic protein BCL-2 compared with acinar cells not (57), suggesting that acinar cells are more susceptible to apoptosis