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This indicates the importance of the p53 TAD2 region in FOXO4 FHD binding

Ahamad N, Bhardwaj P, Bhatia E, Banerjee R

for example, ferroptotic stress may cause disruptions in the endothelial barrier function and recruitment of leukocytes, induce macrophage/foam cell death resulting in the growth of the necrotic core as well as amplify oxidized lipids when there is defective efferocytosis, and induce vascular smooth muscle cell loss leading to compromised fibrous cap integrity and increased rupture susceptibility

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Biochimica et Biophysica Acta (BBA)Molecular Cell Research, 1499(12), 144153

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