glutathione genetic defect reductase Glutathione: Master Antioxidant, Reducing Oxidative

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2020;208 doi: 10.1016/j.pharmthera.2020.107494

These results are not unprecedentedour lab has shown that some RNA viruses target host mRNAs encoding isoforms of thioredoxin reductase via RNA:RNA antisense interactions, which, like proteolysis, would likely also result in host selenoprotein knockdown, but by a different mechanism ( Understanding why RNA viruses may have developed such strategies presents an interesting challenge for future research