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Mee-inta O, Zhao Z-W, Kuo Y-M

32 It has been reported that ATM plays an important role in activating apoptosis and downstream elements of DNA repair, such as p53 and Chk1

doi: 10.1002/mrd.23116

The third reaction is the oxidative decarboxylation of 6-phosphogluconate, which is catalyzed by 6-phosphogluconate dehydrogenase (6PGDH), to yield a second NADPH and ribulose-5-phosphate (Ru5P), which is then converted to ribose-5-phosphate (R5P) (Fig

Keap1 adduct formation changes the conformation of Keap1, leading to the Keap1-Nrf2 dissociation, as well as leading to Keap1 ubiquitination and degradation [37]

Curcumin reactivates silenced tumor suppressor gene RAR by reducing DNA methylation