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When Pycnogenol was compared with a Gn-RH agonist in women with endometriosis, Pycnogenol reduced pain scores over time [161]

Notch signaling in development, tissue homeostasis, and disease

PMID: 134 WuMZhangXZhangWChiouYSQianWLiuXet al

doi: 10.1016/j.cca.2018.06.031 9

Zhu adds, considering that keratinocytes are the major skin cell type in which HSV replicates in patients, the fact that acyclovir isnt all that potent at suppressing HSV in this cell type may explain why it isnt always effective in treating HSV flare-ups! Looking forward, the team is excited to follow up on some of their top antiviral candidates and keep developing their organoid models, whose utility in deciphering cell type-specific differences in antiviral effectiveness is now clear

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