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Disrupted cortisol patterns help explain many of the symptoms long COVID patients consistently report, including: Fatigue Sleep dysfunction Inflammatory amplification Poor stress resilience Gut Microbiome Disruption COVID-19 causes significant gut microbiome disruption during acute infection, and research shows this disruption can persist for months in long COVID patients

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[DOI] [PubMed] [Google Scholar] 260.Mazze R.I., Dunbar R.W

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