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[DOI] [PubMed] [Google Scholar] 44.Reddy V.N

Origin of cadmium-induced reactive oxygen species production: Mitochondrial electron transfer versus plasma membrane NADPH oxidase

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In the case of eNOS uncoupling due to relative intracellular BH 4 deficiency, this phenomenon could be prevented by simultaneous overexpression of the BH 4 synthesizing enzyme GTP cyclohydrolase I, which has been demonstrated in isolated cells 92 and in atherosclerotic animal models