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Capmatinib (INC280) is active against models of nonsmall cell lung cancer and other cancer types with defined mechanisms of MET activation
Increased cystine uptake, via the increased expression of the SCL7A11 transporter, has been shown to contribute to changes in the epigenome
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Malate is then shuttled out of mitochondria to the cytosol whereby it is converted back to pyruvate
Kel'el Ware now has an NBA honor that even Dwyane Wade went without during his rookie season with the Miami Heat
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