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Oxidative stress is characterized by an imbalance between prooxidant species (e.g., reactive oxygen species (ROS) and reactive nitrogen species (RNS) that promote oxidation, and antioxidant enzymes (e.g., GPX and transferrin) that inhibit this oxidation

Research frontiers The main focus of the intervention was that BPC 157 rapidly activates collaterals due to its particular direct and rapid effect on vessel presentation, the bypassing of one or more of the vascular obstructions and thereby achieving a therapeutic effect

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A number of studies have shown that antioxidants protect dopaminergic cells from the toxicity of Complex I inhibitors [26, 159, 167, 191, 266]

2.2.1.1 Endogenous free radical trapping antioxidants Vitamin E and the trace mineral selenium ( Se ) form a complementary antioxidant system (Saito, 2021)

By modulating mitochondrial dynamics, antioxidant defences, protein-quality control, stress responses and multiple signalling cascades, it emerges as a compelling therapeutic target for diseases driven by redox imbalance, protein misfolding and inflammation (Fig