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Figure 6 3.2.3 Microbial markers and therapeutic correlates A cross-sectional study has found that taking atypical antipsychotics (AAPs) led to an increase in a group of gut bacteria called Lachnospiraceae and a decrease in Akkermansia, which is often linked to gut health ( Faecalibacterium , a beneficial bacterium known for producing butyrate a short-chain fatty acid important for gut health

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Boosted Collagen and Elastin Production : The growth factors in exosomes stimulate fibroblast activity, which increases collagen and elastin production

If Steroids Fail (no improvement after 4872 hrs) Consider adding: IVIG (2 g/kg over 5 days) Infliximab (TNF- inhibitor requires TB/hepatitis screening) Mycophenolate mofetil (11.5 g/day BID or TID, start at effective dose quickly) IVIG may have lower mortality in some series but comes with risks (volume overload, thrombosis, infusion reactions)

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