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doi:10.1016/j.jflm.2018.02.026

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Mechanisms of antidiabetic effects of flavonoid rutin

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There was evidence that mice without efficient expression of SOD2 enzyme resulted in significant epidermal thinning. In humans mitochondrial dysfunction promotes cellular senescence in epidermal keratinocytes in culture. [7] This means because of senescence, there were fewer cells in the epidermis, causing it to be thinner

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