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Ohanian M, Kantarjian HM, Borthakur G , Kadia TM, Konopleva M, Garcia-Manero G, Estrov Z, Ferrajoli A, Takahashi K, Jabbour EJ, Daver N, Kornblau SM, Wierda WG, Burger JA, Naqvi K, Benton CB, Bose P, Eckardt JR, Ravandi F, Cortes JE

When administered at doses of 0, 0.1, 0.25, and 0.5 ug/mL, growth hormone receptor expression was increased in a dose-dependent manner

Under obese or diet-induced diabetic conditions, mTORC1 activity is generally upregulated in many organs and tissues

Nature 510 , 109114 (2014)

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Two small case-control studies analyzed the association of the Pro198Leu (rs1050450) polymorphism with AD, with different results