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Description
By inhibiting NNMT and preserving NAD, 5-Amino-1MQ indirectly boosts SIRT1 activity , leading to: Increased fat oxidation SIRT1 activates PGC-1 (peroxisome proliferator-activated receptor gamma coactivator 1-alpha), a master regulator of mitochondrial biogenesis and fat metabolism
[DOI] [PMC free article] [PubMed] [Google Scholar] 9.Vukojevic J., Milavic M., Perovic D., Ilic S., Cilic A.Z., Duran N., Strbe S., Zoricic Z., Filipcic I., Brecic P., et al
doi: 10.1038/cddis.2013.178 129 GargSWangWPrabathBGBoermaMWangJZhouDet al
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