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The lens of the eye is particularly susceptible to glycation reactions, in which high glucose concentrations damage proteins and contribute to tissue dysfunction (Jain 2002

[DOI] [PMC free article] [PubMed] [Google Scholar] 1095.Ruiz H.H., Nguyen A., Wang C., He L., Li H., Hallowell P., McNamara C., Schmidt A.M

[DOI] [PMC free article] [PubMed] [Google Scholar] 286.Roncati L., Manenti A., Pusiol T., Piscioli F., Barbolini G., Maiorana A

Cells neutralize ROS via the action of various enzyme complexes, some of which ultimately result in the oxidation of reduced GSH to the oxidized form of glutathione, GSSG 20

Choose injection site & wipe with alcohol swab Step 5

Concurrently, ROS can activate key inflammatory signaling pathways such as NF-B [477]