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Liu J, Head E, Gharib AM, Yuan W, Ingersoll RT, Hagen TM, Cotman CW, Ames BN: Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: partial reversal by feeding acetyl-L-carnitine and/or R-alpha -lipoic acid

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[DOI] [PMC free article] [PubMed] [Google Scholar] 164.Huycke MM, Joyce W, Wack MF

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Oxidative phosphorylation, not glycolysis, powers presynaptic and postsynaptic mechanisms underlying brain information processing

These synthetic vitamins, in excessive amounts, may act as pro-oxidants, which can potentially do more harm than good