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EGFR TKIs are expressed in keratinocytes, hair follicles, and sebaceous glands, so their inhibition results in disruption of the skin barrier, abnormal keratinization, and follicular inflammation mediated by IL-8, which generates acneiform rash and paronychia [15, 16]
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[DOI] [PubMed] [Google Scholar] 30.Wachter S., Vogt M., Kreis R., Boesch C., Bigler P., Hoppeler H., Krahenbuhl S
