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Arginase 1 (cytosolic isoform) expression in MDSCs is also important for the suppressive function of these cells, restraining Teffs-mediated antitumor immunity and promoting both Teffs cell death and Tregs suppressive effects [85, 86]

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Lyophilisation is a complex freeze-drying process that removes water from a biological or chemical sample while preserving its molecular structure

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Legalities Its legal status varies by country