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PMID: 40885724 Acta Pharm Sin B2025 Aug;15(8):4078-4095
The plant Mo-hydroxylases aldehyde oxidase and xanthine dehydrogenase have distinct reactive oxygen species signatures and are induced by drought and abscisic acid

J Biol Chem 291:2294922960 Jalali M, Mahmoodi M, Mosallanezhad Z, Jalali R, Imanieh MH, Moosavian SP (2020) The effects of curcumin supplementation on liver function, metabolic profile and body composition in patients with non-alcoholic fatty liver disease: a systematic review and meta-analysis of randomized controlled trials

Results Glutamine metabolism genes are upregulated in PDA Enzymes utilized for glutamine metabolism in PDA, GLS1 , GOT1/2 , and malic enzyme 1 ( ME1 ) (see pathway, Fig

The beads were then washed three times with ice-cold IP buffer

Therefore, our findings suggest that pyroptosis of synovial macrophages plays a role in inducing inflammation in synovial chondrocytes and targeting synovial macrophages may be a potential therapeutic strategy for OA management
