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In addition, exogenous IGF-1 administration has been shown to reduce serum glucose levels [95, 143, 144], not only in healthy individuals [140, 145147], but also in those with insulin resistance [148, 149], type I [150152], and T2D [153155]

Clinical trial population adjacent: Obese individuals with higher adiposity, MASLD, T2D/high HbA1c, and/or significant liver fat and metabolic panel improvement goals

Insert the needle into the vial and push the air in

SubQ is also lower-skill, less painful, and lower-risk than IM: the fat layer has few large blood vessels and nerves, so the odds of a painful or bloody injection are lower

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Weeks 9-12: 7.5mg (0.75mL or 75 units)