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Invest 127 , 26782688 (2017)

[DOI] [PubMed] [Google Scholar] 225.Manda K

First draft prepared by Dr

En cultivos de adipocitos, la inhibicin de NNMT con este compuesto se ha asociado con incremento de NAD+ intracelular, activacin de AMPK y aumento de la beta-oxidacin de lpidos, reduciendo el tamao de las gotas lipdicas en modelos celulares

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We found that significant apoptosis and impaired mitochondrial (cristae were markedly decreased and density was increased) in MM.1 S when deficiency of PRDX6 (Fig