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Notably, incubating peripheral whole blood cultures with vitamin B12 resulted in the normalization of CCL11 expression, the increase of the neuroprotective HGF and the decrease CSF2 and CXCL10 mRNA levels in leukocytes from individuals with persistent VCD (Fig

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Neurologic manifestations will not be prevented with folic acid, and if not treated with vitamin B12, irreversible damage will result