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Moreover, the choice of behavioral tests varies substantially across studies, which further complicates the interpretation of antioxidant effects
CTR1 over-expression or functional impairment of ATP7A/7B breaks this loop, allowing copper to accumulate and penetrate mitochondria, thereby priming cuproptosis

19 , e7 (2017)

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Combination of FLT3 Inhibitor Quizartinib and MDM2 Inhibitor Milademetan Results in Greater Pre-Clinical Anti-Leukemic Activity in FLT3-ITD Mutant/P53 Wild-Type Acute Myeloid Leukemia Models
