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Interestingly, ursodeoxycholic acid, the only treatment approved by the Food and Drug Administration for the treatment of primary biliary cirrhosis, a chronic cholestatic disorder, was shown to prevent the fall in GCL expression during chronic cholestasis (Serviddio et al., 2004) and increase GCL expression in cultured rat hepatocytes (Mitsuyoshi et al., 1999)

For extended storage periods, we recommend freezer conditions to maintain long-term stability

Given this variability, a conservative approach is wise: assume the shorter end of the spectrum and store as best as possible

In animal and preclinical studies, it is associated with tissue-protective effects, modulation of inflammatory signaling, and support of angiogenesis and tendon-to-bone healing pathways

Good hygiene, a fresh single-use needle and safe disposal remove most of that risk

Dosage: o Cattle: 8 to 10ml alternative day for 7 days