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Glutathione is an endogenous redox couple in animal cells and plays important roles in antioxidant defense and detoxification, although it is unknown if oral glutathione supplementation affects exercise-induced physiological changes

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By elucidating the critical roles of ROS homeostasis in cellular physiology and disease treatment, this review aims to advance the discovery of potential biomarkers as well as the development of novel therapeutic approaches based on ROS homeostasis.