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doi: 10.7759/cureus.21476

Ongoing studies are aimed at determining the potential relevance of NNMT inhibition to cognitive performance and neurological research

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Older age : Due to changes in dietary nutrient intake (usually from eating less overall) and also decreased production of stomach acid, the elderly tend to have reduced levels of vitamin B12

doi:10.1016/j.bcp.2019.02.008 Dimet-Wiley A, Latham CM, Brightwell CR, et al

Elevation of NAD Levels One of the most important downstream effects of NNMT inhibition by 5-Amino-1MQ is the preservation and elevation of nicotinamide adenine dinucleotide (NAD)
