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Overexpressed methyltransferase-like 1 (METTL1) increased chemosensitivity of colon cancer cells to cisplatin by regulating miR-149-3p/S100A4/p53 axis

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Discussion In this study, we identified the RhoGEF Ect2 as a novel component of the cardiac ID and keratinocyte desmosomes, which is required for the maintenance of an active pool of RhoA at IDs

For example Cisplatin is used along with honey venom (Alizadehnohi, Nabiuni et al., 2012), withaferin (Kakar, Jala et al., 2012), trichostatin A or 5-aza-2-deoxycytidine (Meng, Sun et al., 2013), overcoming chemotherapy resistance of ovarian cancer cells by liposomal Cisplatin (Koch, Krieger et al., 2013) 3.3

Nicotinamide adenine dinucleotide (NAD+), a coenzyme found in all living cells, and central to endothelial health and energy metabolism