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Efficacy of the 2 -adrenergic receptor is determined by conformational equilibrium in the transmembrane region

Mitochondrial retrograde signals such as ATP levels, ROS and Ca 2+ modulate intracellular signaling cascades, affecting mitochondrial biogenesis [70]

Li, L.-H

Am J Physiol Cell Physiol (2007) 292(4):C122139.10.1152/ajpcell.00263.2006 24 GenovaMLenazG

demonstrated that iron chelators inhibit the Fe 2 -mediated Fenton reaction, thereby preventing oxidative damage (Ou et al