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Description
They include enzymatic degradation by proteases or peptidases, low permeability across the mucosal epithelium, and rapid clearance due to salivary dynamics

S., Dickerson F., Boronow J., Hibbeln J

doi:10.1097/01.jom.0000177336.21147.9f

When the issues with benzodiazepine side effects, tolerance, and/or interdose withdrawal have been identified, there are some options each patient can consider: The first is switching to a longer half-life drug using a reputable, experience-based conversion table, such as The Ashton Manual, to address interdose withdrawal

Metal ions in Biological Systems

Unfortunately the effects of intramuscular injections are quite confusing to parents and clinicians