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Then, PARKIN and ubiquitin are phosphorylated, resulting in the assembly of ubiquitin-linked chains K6-, K11-, K48-, and K63- on the OMM (Heo et al., 2015)

People with lower CYP1A2 activity may generate reactive aflatoxin metabolites more slowly (could be a good thing), but they can still be vulnerable if downstream conjugation pathways (GSTs, UGTs) are also compromised.[ref] Related article: CYP1A2 Gene: Fast or Slow Caffeine Metabolizer and More CYP3A4 and aflatoxin G1 / other mycotoxins: CYP3A4 is involved in the metabolism of aflatoxin G1 and many other compounds, including medications

J Fosmire G The impaired growth induced by zinc deficiency in rats is associated with decreased expression of the hepatic IGF-I and the growth hormone receptor genes

Association of mast cells with fibrosis and fatty infiltration in the minor salivary glands of patients with Sjgren's syndrome

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2001;25(Suppl