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In addition, another study conducted by Herman et al

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J Agric Food Chem 50(2):313318 Chang HP, Liang WC, Lyu RC, Chi MC, Wang TF, Su KL, Hung HC, Lin LL (2010) Effects of C-terminal truncation on autocatalytic processing of Bacillus licheniformis gamma-glutamyl transpeptidase

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Thus, during short-term fasting, changes in free and bioactive IGF-I rather than total IGF-I appear to be at least in part responsible for the increased GH secretion (111, 112), intermittent fasting (113), nor long-term calorie restriction (114) exerts any consistent inhibitory impact on serum IGF-I levels