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doi: 10.1002/adhm.201600967 192 ChenMZhangYZhouPLiuXZhaoHZhouXet al

Side effects associated with tesofensine may include the following: Studies have indicated that the tesofensine dosage range employed was between 0.25 mg to 1 mg

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It competitively binds p53, displacing endogenous FOXO4 in senescent cells (Baar et al., 2017) 24-72 hours: Freed p53 translocates to mitochondria in senescent cells, triggering the intrinsic apoptotic cascade

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