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Early and precise diagnosis of PH is clinical challenge and still relies on invasive examination- right heart catheterization [3]

Tse, C., Sera, T., Wolffe, A

L-Carnitine is a molecule that the body uses to transport fat into cells and mitochondria for energy production

Fourth, MR requires stringent assumptions, i.e., the genetic variants are associated with the exposure, no confounders of the associations of the genetic variants with the outcomes exist, and the genetic variants are not associated with the outcomes other than via affecting the relevant exposure (no pleiotropy) [17]

Consistently, both RTT patients and Mecp2- mutant mice present with increased oxidative stress and decreased levels of mitochondrial enzymes (Haas et al

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