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Mushrooms are typically the richest source of ergothioneine in the human diet, with amounts of ergothioneine varying wildly depending on strain and growing conditions (Reference Halliwell, Cheah and Tang17)

The study also used Western blot analysis to detect potential expressions of phosphorylated tau, a protein associated with neurodegenerative diseases

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Furthermore, sourcing introduces uncertainty in sterility and formulation integrity, which may represent a more immediate and clinically relevant risk than theoretical biologic effects, particularly given the potential for nonsterile preparation, contamination, or inconsistent formulation in nonregulated injectable products

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